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Tytuł: Effects of brief whole-body vibration on bone metabolic and immunological indices in rats

Alicja Nowak, Maciej Pawlak, Martyna Brychcy, Jan Celichowski, Piotr Krutki
Studies in Physical Culture and Tourism
Strona początkowa:
Strona końcowa:
Słowa kluczowe:
whole-body vibration, bone turnover, inflammation, rat, BMD.

Introduction. Numerous studies have focused on the musculo-skeletal effects on high-frequency vibration programs; however, bone tissue responses to brief sessions of intensive WBV stimulation have been less recognized. Aim of Study. The study examined whether short-lasting whole-body vibration (WBV) was sufficient to induce bone metabolic and immunological response, and whether the increasing volume of vibration training modifies changes in bone and modulate immunological indices. Material and Methods. Ten male Wistar rats, aged 6 months, were subjected to 5-week WBV (5 days/ /week, frequency 50 Hz, amplitude of oscillations 2.5 mm). Five animals underwent vibration training in a single session lasting 30 seconds (WBV30), while the other five were subjected to four vibration sessions of 30 seconds each, separated by 60-second rest intervals (WBV30x4). Results were compared with those of age-matched controls (n = 5). Results. No significant vibration-related changes in bone mineral density or between-groups differences in serum concentrations of osteocalcin and C-terminal telopeptide of type I collagen after the vibration program were found in either group of animals. Significant differences were found in the soluble receptor activator of nuclear factor kappa-B ligand levels between animals in the WBV30 group and controls as well as in interleukin-10 concentrations between the WBV30x4 group and controls. Conclusions. The brief vibration programs, especially with the higher WBV volume, were sufficient to induce metabolic response. The lack of vibration-related changes in bone mass and between-groups differences in concentrations of bone turnover markers does not permit drawing prospective conclusions with respect to bone tissue.